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SMARCB1-Deficient Cancers: Novel Molecular Insights and Therapeutic Vulnerabilities
SIMPLE SUMMARY: Loss of SMARCB1 has been identified as the sole mutation in a number of rare pediatric and adult cancers, most of which have a poor prognosis despite intensive therapies including surgery, radiation, and chemotherapy. Thus, a more robust understanding of the mechanisms driving this s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332782/ https://www.ncbi.nlm.nih.gov/pubmed/35892904 http://dx.doi.org/10.3390/cancers14153645 |