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SMARCB1-Deficient Cancers: Novel Molecular Insights and Therapeutic Vulnerabilities

SIMPLE SUMMARY: Loss of SMARCB1 has been identified as the sole mutation in a number of rare pediatric and adult cancers, most of which have a poor prognosis despite intensive therapies including surgery, radiation, and chemotherapy. Thus, a more robust understanding of the mechanisms driving this s...

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Detalles Bibliográficos
Autores principales: Cooper, Garrett W., Hong, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332782/
https://www.ncbi.nlm.nih.gov/pubmed/35892904
http://dx.doi.org/10.3390/cancers14153645

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