SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane

Serine incorporator 5 (SER5) is a protein that upon incorporation into virions inhibits HIV-1 infectivity by interfering with the ability of the Env glycoprotein to promote viral fusion. The mechanisms by which SER5 antagonizes HIV-1 fusion are not well understood. A recent study of SER5’s structure...

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Detalles Bibliográficos
Autores principales: Raghunath, Gokul, Chen, Yen-Cheng, Marin, Mariana, Wu, Hui, Melikyan, Gregory B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332783/
https://www.ncbi.nlm.nih.gov/pubmed/35893701
http://dx.doi.org/10.3390/v14081636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332783/
https://www.ncbi.nlm.nih.gov/pubmed/35893701
http://dx.doi.org/10.3390/v14081636

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