COX-2/sEH Dual Inhibitor Alleviates Hepatocyte Senescence in NAFLD Mice by Restoring Autophagy through Sirt1/PI3K/AKT/mTOR

We previously found that the disorder of soluble epoxide hydrolase (sEH)/cyclooxygenase-2 (COX-2)-mediated arachidonic acid (ARA) metabolism contributes to the pathogenesis of the non-alcoholic fatty liver disease (NAFLD) in mice. However, the exact mechanism has not been elucidated. Accumulating ev...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chen-Yu, Tan, Xiao-Hua, Yang, Hui-Hui, Jin, Ling, Hong, Jie-Ru, Zhou, Yong, Huang, Xiao-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332821/
https://www.ncbi.nlm.nih.gov/pubmed/35897843
http://dx.doi.org/10.3390/ijms23158267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332821/
https://www.ncbi.nlm.nih.gov/pubmed/35897843
http://dx.doi.org/10.3390/ijms23158267

Ejemplares similares