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A Multi-Scale Approach to Model K(+) Permeation Through the KcsA Channel

K(+) channels allow a very efficient passage of K(+) ions through the membrane while excluding Na(+) ions, and these properties are essential for life. The 3D structure of the KcsA K(+) channel, solved more than 20 years ago, allows to address many relevant aspects of K(+) permeation and selectivity...

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Detalles Bibliográficos
Autores principales: Horng, T. L., Chen, R. S., Leonardi, M. V., Franciolini, F., Catacuzzeno, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332843/
https://www.ncbi.nlm.nih.gov/pubmed/35911957
http://dx.doi.org/10.3389/fmolb.2022.880660