Prognostic impact of PDGFRA gain/amplification and MGMT promoter methylation status in patients with IDH wild-type glioblastoma

BACKGROUND: Platelet-derived growth factor receptor alpha (PDGFRA) is the second most frequently mutated tyrosine kinase receptor in glioblastoma (GBM). However, the prognostic impact of PDGFRA amplification on GBM patients remains unclear. Herein, we evaluated this impact by retrospectively analyzi...

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Detalles Bibliográficos
Autores principales: Higa, Nayuta, Akahane, Toshiaki, Yokoyama, Seiya, Yonezawa, Hajime, Uchida, Hiroyuki, Takajo, Tomoko, Otsuji, Ryosuke, Hamada, Taiji, Matsuo, Kei, Kirishima, Mari, Hata, Nobuhiro, Hanaya, Ryosuke, Tanimoto, Akihide, Yoshimoto, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332894/
https://www.ncbi.nlm.nih.gov/pubmed/35911637
http://dx.doi.org/10.1093/noajnl/vdac097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332894/
https://www.ncbi.nlm.nih.gov/pubmed/35911637
http://dx.doi.org/10.1093/noajnl/vdac097

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