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P2X7 Purinoceptor Affects Ectopic Calcification of Dystrophic Muscles

Ectopic calcification (EC) of myofibers is a pathological feature of muscle damage in Duchenne muscular dystrophy (DMD). Mineralisation of muscle tissue occurs concomitantly with macrophage infiltration, suggesting a link between ectopic mineral deposition and inflammation. One potential link is the...

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Detalles Bibliográficos
Autores principales: Rumney, Robin M. H., Róg, Justyna, Chira, Natalia, Kao, Alexander P., Al-Khalidi, Rasha, Górecki, Dariusz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333129/
https://www.ncbi.nlm.nih.gov/pubmed/35910348
http://dx.doi.org/10.3389/fphar.2022.935804