Discovery of 2-Phenylquinoline-4-Carboxylic Acid Derivatives as Novel Histone Deacetylase Inhibitors

Inhibition of histone deacetylases (HDACs) has been extensively studied in the development of anticancer drugs. In the discovery of potent HDAC inhibitors with novel structures, the 2-substituted phenylquinoline-4-carboxylic acid group was introduced to the cap moiety of HDAC inhibitors. In total, 3...

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Detalles Bibliográficos
Autores principales: Hui, Qian, Zhang, Lihui, Feng, Jinhong, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333195/
https://www.ncbi.nlm.nih.gov/pubmed/35910736
http://dx.doi.org/10.3389/fchem.2022.937225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333195/
https://www.ncbi.nlm.nih.gov/pubmed/35910736
http://dx.doi.org/10.3389/fchem.2022.937225

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