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Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells

Inflammatory signaling induces barrier dysfunction in retinal-pigmented epithelium (RPE) cells and plays a role in the pathology of age-related macular degeneration (AMD). We studied the role of Zn flux from the endoplasmic reticulum (ER) to the cytoplasm via Zip7 during inflammatory signaling in RP...

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Detalles Bibliográficos
Autores principales: Xu, YongYao, Twarog, Michael, Li, Ning, Banks, Angela, Schustak, Josh, Bao, Yi, Huang, Qian, Medley, Quintus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333247/
https://www.ncbi.nlm.nih.gov/pubmed/35901031
http://dx.doi.org/10.1371/journal.pone.0271656