Cargando…
Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells
Inflammatory signaling induces barrier dysfunction in retinal-pigmented epithelium (RPE) cells and plays a role in the pathology of age-related macular degeneration (AMD). We studied the role of Zn flux from the endoplasmic reticulum (ER) to the cytoplasm via Zip7 during inflammatory signaling in RP...
Autores principales: | Xu, YongYao, Twarog, Michael, Li, Ning, Banks, Angela, Schustak, Josh, Bao, Yi, Huang, Qian, Medley, Quintus G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333247/ https://www.ncbi.nlm.nih.gov/pubmed/35901031 http://dx.doi.org/10.1371/journal.pone.0271656 |
Ejemplares similares
-
TNFα induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function
por: Twarog, Michael, et al.
Publicado: (2023) -
Mechanism of Nucleic Acid Sensing in Retinal Pigment Epithelium (RPE): RIG-I Mediates Type I Interferon Response in Human RPE
por: Schustak, Joshua, et al.
Publicado: (2021) -
Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function
por: Ellis, Charissa D., et al.
Publicado: (2004) -
Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells
por: Minasyan, Leonid, et al.
Publicado: (2017) -
Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione
por: Matsunaga, Douglas, et al.
Publicado: (2016)