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Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH

Transforming growth factor beta (TGF-β) induced myofibroblast differentiation is central to the pathological scarring observed in Idiopathic Pulmonary Fibrosis (IPF) and other fibrotic diseases. Our lab has recently identified expression of GPR68 (Ovarian Cancer Gene Receptor 1, OGR1), a pH sensing...

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Detalles Bibliográficos
Autores principales: Bell, Tyler J., Nagel, David J., Woeller, Collynn F., Kottmann, R. Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333254/
https://www.ncbi.nlm.nih.gov/pubmed/35901086
http://dx.doi.org/10.1371/journal.pone.0271608