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Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH
Transforming growth factor beta (TGF-β) induced myofibroblast differentiation is central to the pathological scarring observed in Idiopathic Pulmonary Fibrosis (IPF) and other fibrotic diseases. Our lab has recently identified expression of GPR68 (Ovarian Cancer Gene Receptor 1, OGR1), a pH sensing...
Autores principales: | Bell, Tyler J., Nagel, David J., Woeller, Collynn F., Kottmann, R. Mathew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333254/ https://www.ncbi.nlm.nih.gov/pubmed/35901086 http://dx.doi.org/10.1371/journal.pone.0271608 |
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