Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice

BACKGROUND: Sorbin and SH3 domain containing 2 (Sorbs2) protein is a cytoskeletal adaptor with an emerging role in cardiac biology and disease; yet, its potential relevance to adult‐onset cardiomyopathies remains underexplored. Sorbs2 global knockout mice display lethal arrhythmogenic cardiomyopathy...

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Detalles Bibliográficos
Autores principales: McLendon, Jared M., Zhang, Xiaoming, Matasic, Daniel S., Kumar, Mohit, Koval, Olha M., Grumbach, Isabella M., Sadayappan, Sakthivel, London, Barry, Boudreau, Ryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333371/
https://www.ncbi.nlm.nih.gov/pubmed/35730644
http://dx.doi.org/10.1161/JAHA.122.025687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333371/
https://www.ncbi.nlm.nih.gov/pubmed/35730644
http://dx.doi.org/10.1161/JAHA.122.025687

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