Cargando…

Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart

BACKGROUND: Histidyl dipeptides such as carnosine are present in a micromolar to millimolar range in mammalian hearts. These dipeptides facilitate glycolysis by proton buffering. They form conjugates with reactive aldehydes, such as acrolein, and attenuate myocardial ischemia–reperfusion injury. Alt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Keqiang, Mei, Zhanlong, Zhao, Jingjing, Prodhan, Md Aminul Islam, Obal, Detlef, Katragadda, Kartik, Doelling, Benjamin, Hoetker, David, Posa, Dheeraj Kumar, He, Liqing, Yin, Xinmin, Shah, Jasmit, Pan, Jianmin, Rai, Shesh, Lorkiewicz, Pawel Konrad, Zhang, Xiang, Liu, Siqi, Bhatnagar, Aruni, Baba, Shahid P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333374/ https://www.ncbi.nlm.nih.gov/pubmed/35730646 http://dx.doi.org/10.1161/JAHA.121.023868

Ejemplares similares

Cardiospecific Overexpression of ATPGD1 (Carnosine Synthase) Increases Histidine Dipeptide Levels and Prevents Myocardial Ischemia Reperfusion Injury
por: Zhao, Jingjing, et al.
Publicado: (2020)

Metabolic Pathways for Removing Reactive Aldehydes are Diminished in Atrophic Muscle During Heart Failure
por: Chaudhari, Mamata, et al.
Publicado: (2023)

Skeletal muscle analysis of cancer patients reveals a potential role for carnosine in muscle wasting
por: Posa, Dheeraj Kumar, et al.
Publicado: (2023)

Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells
por: Conroy, Lindsey R., et al.
Publicado: (2020)

Unusually Fast bis-Histidyl Coordination in a Plant Hemoglobin
por: Abbruzzetti, Stefania, et al.
Publicado: (2021)

The emerging roles of ribosomal histidyl hydroxylases in cell biology, physiology and disease
por: Bundred, James R., et al.
Publicado: (2018)

Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates
por: Turkez, Hasan, et al.
Publicado: (2020)

Distribution based nearest neighbor imputation for truncated high dimensional data with applications to pre-clinical and clinical metabolomics studies
por: Shah, Jasmit S., et al.
Publicado: (2017)

Circulating angiogenic stem cells in type 2 diabetes are associated with glycemic control and endothelial dysfunction
por: Zafar, Nagma, et al.
Publicado: (2018)

Thermodynamic and Structural Characterization of the Copper(II) Complexes of Peptides Containing Both Histidyl and Aspartyl Residues
por: Kállay, Csilla, et al.
Publicado: (2007)

Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
por: Tian, Qingnan, et al.
Publicado: (2015)

Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth
por: Lee, Weon Ju, et al.
Publicado: (2016)

Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth
por: Gibb, Andrew A., et al.
Publicado: (2017)

A noncanonical function of histidyl‐tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development
por: Ni, Rui, et al.
Publicado: (2018)

Synthesis of Caffeoyl-Prolyl-Histidyl-Xaa Derivatives and Evaluation of Their Activities and Stability upon Long-Term Storage
por: Jeong, Hyeri, et al.
Publicado: (2021)

Metabolomics data analysis and missing value issues with application to infarcted mouse hearts
por: Shah, Jasmit S, et al.
Publicado: (2015)

TFAM detects co-evolution of tRNA identity rules with lateral transfer of histidyl-tRNA synthetase
por: Ardell, David H., et al.
Publicado: (2006)

Interference with histidyl-tRNA synthetase by a CRISPR spacer sequence as a factor in the evolution of Pelobacter carbinolicus
por: Aklujkar, Muktak, et al.
Publicado: (2010)

A single Danio rerio hars gene encodes both cytoplasmic and mitochondrial histidyl-tRNA synthetases
por: Waldron, Ashley L., et al.
Publicado: (2017)

Correction: A single Danio rerio hars gene encodes both cytoplasmic and mitochondrial histidyl-tRNA synthetases
por: Waldron, Ashley L., et al.
Publicado: (2018)

Knock-Down of Histidyl-tRNA Synthetase Causes Cell Cycle Arrest and Apoptosis of Neuronal Progenitor Cells in vivo
por: Waldron, Ashley, et al.
Publicado: (2019)

Detecting and measuring of GPCR signaling – comparison of human induced pluripotent stem cells and immortal cell lines
por: Chen, Gaoxian, et al.
Publicado: (2023)

Carnosine Supplementation Enhances Post Ischemic Hind Limb Revascularization
por: Boakye, Adjoa A., et al.
Publicado: (2019)

Statistical design of Phase II/III clinical trials for testing therapeutic interventions in COVID-19 patients
por: Rai, Shesh N., et al.
Publicado: (2020)

Change of tRNA identity leads to a divergent orthogonal histidyl-tRNA synthetase/tRNA(His) pair
por: Yuan, Jing, et al.
Publicado: (2011)

Suppression of Amber Codons in Caulobacter crescentus by the Orthogonal Escherichia coli Histidyl-tRNA Synthetase/tRNA(His) Pair
por: Ko, Jae-hyeong, et al.
Publicado: (2013)

Frequency of dipeptides and antidipeptides
por: Carugo, Oliviero
Publicado: (2013)

Histidyl–tRNA Synthetase and Asparaginyl–tRNA Synthetase, Autoantigens in Myositis, Activate Chemokine Receptors on T Lymphocytes and Immature Dendritic Cells
por: Howard, O.M. Zack, et al.
Publicado: (2002)

Improved laccase production by Trametes versicolor using Copper-Glycyl-L-Histidyl-L-Lysine as a novel and high-efficient inducer
por: Wang, Feng, et al.
Publicado: (2023)

Antigen-driven T cell-macrophage interactions mediate the interface between innate and adaptive immunity in histidyl-tRNA synthetase-induced myositis
por: Reay, Daniel P., et al.
Publicado: (2023)

Cyclic Dipeptides Formation From Linear Dipeptides Under Potentially Prebiotic Earth Conditions
por: Guo, Yeting, et al.
Publicado: (2021)

Glycyl-L-histidyl-L-lysine-Cu(2+) attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway
por: Zhang, Qin, et al.
Publicado: (2022)

Elucidating effects of environmental exposure using human‐induced pluripotent stem cell disease modeling
por: Chandy, Mark, et al.
Publicado: (2022)

Action of Cathepsin C on Dipeptide Esters
por: Wiggans, Donald S., et al.
Publicado: (1954)

Central pyrogenic activity of muramyl dipeptide
Publicado: (1980)

Synthesis and Modifications of Phosphinic Dipeptide Analogues
por: Mucha, Artur
Publicado: (2012)

Effect of Homochirality of Dipeptide to Polymers’ Degradation
por: Xu, Xinqiang, et al.
Publicado: (2020)

Urinary Levels of the Acrolein Conjugates of Carnosine Are Associated with Cardiovascular Disease Risk
por: O’Toole, Timothy E., et al.
Publicado: (2021)

2-Oxo-Imidazole-Containing Dipeptides Play a Key Role in the Antioxidant Capacity of Imidazole-Containing Dipeptides
por: Kasamatsu, Shingo, et al.
Publicado: (2021)

Thermodynamics of semi-specific ligand recognition: the binding of dipeptides to the E.coli dipeptide binding protein DppA
por: Zainol, Mohamad K. M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bksic4uv3qqrpk461vf8rpb7ho