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Colchicine Ameliorates Dilated Cardiomyopathy Via SIRT2‐Mediated Suppression of NLRP3 Inflammasome Activation

BACKGROUND: Dilated cardiomyopathy remains a leading cause of heart failure worldwide. Immune inflammation response is recognized as a significant player in the progression of heart failure; however, immunomodulatory strategies remain a long‐term challenge. Colchicine, a potent anti‐inflammatory dru...

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Detalles Bibliográficos
Autores principales: Sun, Xuan, Duan, Junfeng, Gong, Chenyi, Feng, Yuting, Hu, Jiaxin, Gu, Rong, Xu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333380/
https://www.ncbi.nlm.nih.gov/pubmed/35766262
http://dx.doi.org/10.1161/JAHA.122.025266