Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice

BACKGROUND: Mice with cardiomyocyte‐specific deletion of Bmal1, a core clock gene, had spontaneous abnormal cardiac metabolism, dilated cardiomyopathy, and shortened lifespan. However, the role of cardiomyocyte Bmal1 in pressure overload induced cardiac remodeling is unknown. Here we aimed to unders...

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Detalles Bibliográficos
Autores principales: Liang, Qing, Xu, Hu, Liu, Min, Qian, Lei, Yan, Jin, Yang, Guangrui, Chen, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333388/
https://www.ncbi.nlm.nih.gov/pubmed/35730615
http://dx.doi.org/10.1161/JAHA.121.025021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333388/
https://www.ncbi.nlm.nih.gov/pubmed/35730615
http://dx.doi.org/10.1161/JAHA.121.025021

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