An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol, and Penicillin G

Violative chemical residues in edible tissues from food-producing animals are of global public health concern. Great efforts have been made to develop physiologically based pharmacokinetic (PBPK) models for estimating withdrawal intervals (WDIs) for extralabel prescribed drugs in food animals. Exist...

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Detalles Bibliográficos
Autores principales: Chou, Wei-Chun, Tell, Lisa A, Baynes, Ronald E, Davis, Jennifer L, Maunsell, Fiona P, Riviere, Jim E, Lin, Zhoumeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biotransformation, Toxicokinetics, and Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333411/
https://www.ncbi.nlm.nih.gov/pubmed/35642931
http://dx.doi.org/10.1093/toxsci/kfac056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333411/
https://www.ncbi.nlm.nih.gov/pubmed/35642931
http://dx.doi.org/10.1093/toxsci/kfac056

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