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Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex

The conserved shelterin complex caps chromosome ends to protect telomeres and regulate telomere replication. In fission yeast Schizosaccharomyces pombe, shelterin consists of telomeric single- and double-stranded DNA-binding modules Pot1-Tpz1 and Taz1-Rap1 connected by Poz1, and a specific component...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Wu, Zhenfang, Zhou, Yuanze, Lu, Yanjia, Lu, Huaisheng, Chen, Hongwen, Shi, Shaohua, Zeng, Zhixiong, Wu, Jian, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333443/
https://www.ncbi.nlm.nih.gov/pubmed/35849625
http://dx.doi.org/10.1371/journal.pgen.1010308