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Mucin 1 Inhibits Ferroptosis and Sensitizes Vitamin E to Alleviate Sepsis-Induced Acute Lung Injury through GSK3β/Keap1-Nrf2-GPX4 Pathway

BACKGROUND: Ferroptosis is a nonapoptotic form of programmed cell death, which may be related to the occurrence and development of sepsis-induced acute respiratory distress syndrome (ARDS)/acute lung injury (ALI). Mucin 1 (MUC1) is a kind of macromolecule transmembrane glycoprotein. Previous studies...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Ming, Gong, Fang-Chen, Qi, Xing, Zheng, Yan-Jun, Zheng, Xiang-Tao, Chen, Ying, Yang, Zhi-Tao, Qing-Ye, Mao, En-Qiang, Chen, Er-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334047/
https://www.ncbi.nlm.nih.gov/pubmed/35910848
http://dx.doi.org/10.1155/2022/2405943