DNMT3A Regulates miR-149 DNA Methylation to Activate NOTCH1/Hedgehog Pathway to Promote the Development of Junctional Osteosarcoma

PURPOSE: To investigate the DNMT3A/miR-149/NOTCH1/Hedgehog axis regulating the development of osteosarcoma. METHODS: First, microRNA and mRNA expression microarrays were downloaded from the GEO database for osteosarcoma and differentially expressed microRNAs were analyzed. Subsequently, we collected...

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Detalles Bibliográficos
Autores principales: Cheng, Shigao, Wang, Wanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334075/
https://www.ncbi.nlm.nih.gov/pubmed/35909477
http://dx.doi.org/10.1155/2022/3261213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334075/
https://www.ncbi.nlm.nih.gov/pubmed/35909477
http://dx.doi.org/10.1155/2022/3261213

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