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Turning towards nonimmunoreactive tumors: Evaluation of cancer-associated fibroblasts enables prediction of the immune microenvironment and treatment sensitivity in pancreatic cancer

Increasing evidence has confirmed that cancer-associated fibroblasts (CAFs) recruit and induce regulatory T cells (Tregs) and macrophages but inhibit cytotoxic T lymphocyte infiltration to a certain extent, indicating that CAFs have a significant influence on the immunosuppressive microenvironment....

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Detalles Bibliográficos
Autores principales: Lu, Siyuan, Hua, Jie, Xu, Jin, Wei, Miaoyan, Liang, Chen, Meng, Qingcai, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Shi, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334218/
https://www.ncbi.nlm.nih.gov/pubmed/35950187
http://dx.doi.org/10.1016/j.csbj.2022.07.029