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Turning towards nonimmunoreactive tumors: Evaluation of cancer-associated fibroblasts enables prediction of the immune microenvironment and treatment sensitivity in pancreatic cancer
Increasing evidence has confirmed that cancer-associated fibroblasts (CAFs) recruit and induce regulatory T cells (Tregs) and macrophages but inhibit cytotoxic T lymphocyte infiltration to a certain extent, indicating that CAFs have a significant influence on the immunosuppressive microenvironment....
Autores principales: | Lu, Siyuan, Hua, Jie, Xu, Jin, Wei, Miaoyan, Liang, Chen, Meng, Qingcai, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Shi, Si |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334218/ https://www.ncbi.nlm.nih.gov/pubmed/35950187 http://dx.doi.org/10.1016/j.csbj.2022.07.029 |
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