The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages

The discovery of STING-related innate immunity has recently provided a deep mechanistic understanding of immunopathy. While the detrimental effects of STING during sepsis had been well documented, the exact mechanism by which STING causes lethal sepsis remains obscure. Through single-cell RNA sequen...

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Detalles Bibliográficos
Autores principales: Wu, Jie, Liu, Qinjie, Zhang, Xufei, Tan, Miaomiao, Li, Xuanheng, Liu, Peizhao, Wu, Lei, Jiao, Fan, Lin, Zhaoyu, Wu, Xiuwen, Wang, Xin, Zhao, Yun, Ren, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334269/
https://www.ncbi.nlm.nih.gov/pubmed/35902564
http://dx.doi.org/10.1038/s41419-022-05115-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334269/
https://www.ncbi.nlm.nih.gov/pubmed/35902564
http://dx.doi.org/10.1038/s41419-022-05115-x

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