Cargando…

Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma

The critical role of the tumor immune microenvironment (TIME) in determining response to immune checkpoint inhibitor (ICI) therapy underscores the importance of understanding cancer cell–intrinsic mechanisms driving immune-excluded (“cold”) TIMEs. One such cold tumor is oral cavity squamous cell car...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Yewen, Xie, Tongxin, Wang, Bingbing, Wang, Rong, Cai, Yu, Yuan, Bo, Gleber-Netto, Frederico O., Tian, Xiangjun, Rodriguez-Rosario, Alanis E., Osman, Abdullah A., Wang, Jing, Pickering, Curtis R., Ren, Xiaoyong, Sikora, Andrew G., Myers, Jeffrey N., Rangel, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334280/
https://www.ncbi.nlm.nih.gov/pubmed/35902768
http://dx.doi.org/10.1038/s42003-022-03675-4