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Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma
The critical role of the tumor immune microenvironment (TIME) in determining response to immune checkpoint inhibitor (ICI) therapy underscores the importance of understanding cancer cell–intrinsic mechanisms driving immune-excluded (“cold”) TIMEs. One such cold tumor is oral cavity squamous cell car...
Autores principales: | Shi, Yewen, Xie, Tongxin, Wang, Bingbing, Wang, Rong, Cai, Yu, Yuan, Bo, Gleber-Netto, Frederico O., Tian, Xiangjun, Rodriguez-Rosario, Alanis E., Osman, Abdullah A., Wang, Jing, Pickering, Curtis R., Ren, Xiaoyong, Sikora, Andrew G., Myers, Jeffrey N., Rangel, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334280/ https://www.ncbi.nlm.nih.gov/pubmed/35902768 http://dx.doi.org/10.1038/s42003-022-03675-4 |
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