Cargando…

The 1, 2-ethylenediamine SQ109 protects against tuberculosis by promoting M1 macrophage polarization through the p38 MAPK pathway

Directly Observed Treatment Short-course (DOTs), is an effective and widely recommended treatment for tuberculosis (TB). The antibiotics used in DOTs, are immunotoxic and impair effector T cells, increasing the risk of re-infections and reactivation. Multiple reports suggest that addition of immune-...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Mona, Kumar, Santosh, Singh, Baldeep, Jain, Preeti, Kumari, Anjna, Pahuja, Isha, Chaturvedi, Shivam, Prasad, Durbaka Vijay Raghava, Dwivedi, Ved Prakash, Das, Gobardhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334294/
https://www.ncbi.nlm.nih.gov/pubmed/35902694
http://dx.doi.org/10.1038/s42003-022-03693-2