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The 1, 2-ethylenediamine SQ109 protects against tuberculosis by promoting M1 macrophage polarization through the p38 MAPK pathway
Directly Observed Treatment Short-course (DOTs), is an effective and widely recommended treatment for tuberculosis (TB). The antibiotics used in DOTs, are immunotoxic and impair effector T cells, increasing the risk of re-infections and reactivation. Multiple reports suggest that addition of immune-...
Autores principales: | Singh, Mona, Kumar, Santosh, Singh, Baldeep, Jain, Preeti, Kumari, Anjna, Pahuja, Isha, Chaturvedi, Shivam, Prasad, Durbaka Vijay Raghava, Dwivedi, Ved Prakash, Das, Gobardhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334294/ https://www.ncbi.nlm.nih.gov/pubmed/35902694 http://dx.doi.org/10.1038/s42003-022-03693-2 |
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