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Rapamycin maintains the primordial follicle pool and protects ovarian reserve against cyclophosphamide-induced damage
Any abnormal activation of primordial follicles and subsequent depletion can irreversibly diminish the ovarian reserve, which is one of the major chemotherapy-induced adverse effects in young patients with cancer. Herein, we investigated the effects of rapamycin on the activation and development of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Society for Reproduction and Development
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334315/ https://www.ncbi.nlm.nih.gov/pubmed/35718464 http://dx.doi.org/10.1262/jrd.2022-001 |