Genetically engineered animal models for Marfan syndrome: challenges associated with the generation of pig models for diseases caused by haploinsufficiency

Recent developments in reproductive biology have enabled the generation of genetically engineered pigs as models for inherited human diseases. Although a variety of such models for monogenic diseases are currently available, reproduction of human diseases caused by haploinsufficiency remains a major...

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Detalles Bibliográficos
Autores principales: JACK, Naomi, MUTO, Tomoyuki, IEMITSU, Keigo, WATANABE, Tamaki, UMEYAMA, Kazuhiro, OHGANE, Jun, NAGASHIMA, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2022
Materias:
Opinions and Hypotheses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334321/
https://www.ncbi.nlm.nih.gov/pubmed/35598970
http://dx.doi.org/10.1262/jrd.2022-027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334321/
https://www.ncbi.nlm.nih.gov/pubmed/35598970
http://dx.doi.org/10.1262/jrd.2022-027

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