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Genetically engineered animal models for Marfan syndrome: challenges associated with the generation of pig models for diseases caused by haploinsufficiency
Recent developments in reproductive biology have enabled the generation of genetically engineered pigs as models for inherited human diseases. Although a variety of such models for monogenic diseases are currently available, reproduction of human diseases caused by haploinsufficiency remains a major...
Autores principales: | JACK, Naomi, MUTO, Tomoyuki, IEMITSU, Keigo, WATANABE, Tamaki, UMEYAMA, Kazuhiro, OHGANE, Jun, NAGASHIMA, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334321/ https://www.ncbi.nlm.nih.gov/pubmed/35598970 http://dx.doi.org/10.1262/jrd.2022-027 |
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