Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes

Androgen/androgen receptor (AR) signaling pathways are essential for prostate tumorigenesis. However, the fundamental mechanisms underlying the AR functioning as a tumor promoter in inducing prostatic oncogenesis still remain elusive. Here, we demonstrate that a subpopulation of prostatic Osr1 (odd...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Won Kyung, Olson, Adam W., Mi, Jiaqi, Wang, Jinhui, Lee, Dong-Hoon, Le, Vien, Hiroto, Alex, Aldahl, Joseph, Nenninger, Christian H., Buckley, Alyssa J., Cardiff, Robert, You, Sungyong, Sun, Zijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334353/
https://www.ncbi.nlm.nih.gov/pubmed/35902588
http://dx.doi.org/10.1038/s41467-022-32119-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334353/
https://www.ncbi.nlm.nih.gov/pubmed/35902588
http://dx.doi.org/10.1038/s41467-022-32119-0

Ejemplares similares