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PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus

Exposure to traumatic stress can lead to fear dysregulation, which has been associated with posttraumatic stress disorder (PTSD). Previous work showed that a polymorphism in the PACAP-PAC1R (pituitary adenylate cyclase-activating polypeptide) system is associated with PTSD risk in women, and PACAP (...

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Detalles Bibliográficos
Autores principales: Velasco, E. R., Florido, A., Flores, Á, Senabre, E., Gomez-Gomez, A., Torres, A., Roca, A., Norrholm, S., Newman, E. L., Das, P., Ross, R. A., Lori, A., Pozo, O. J., Ressler, K. J., Garcia-Esteve, L. L., Jovanovic, T., Andero, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334354/
https://www.ncbi.nlm.nih.gov/pubmed/35902577
http://dx.doi.org/10.1038/s41467-022-31442-w