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De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

Cry11Aa and Cry11Ba are the two most potent toxins produced by mosquitocidal Bacillus thuringiensis subsp. israelensis and jegathesan, respectively. The toxins naturally crystallize within the host; however, the crystals are too small for structure determination at synchrotron sources. Therefore, we...

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Detalles Bibliográficos
Autores principales: Tetreau, Guillaume, Sawaya, Michael R., De Zitter, Elke, Andreeva, Elena A., Banneville, Anne-Sophie, Schibrowsky, Natalie A., Coquelle, Nicolas, Brewster, Aaron S., Grünbein, Marie Luise, Kovacs, Gabriela Nass, Hunter, Mark S., Kloos, Marco, Sierra, Raymond G., Schiro, Giorgio, Qiao, Pei, Stricker, Myriam, Bideshi, Dennis, Young, Iris D., Zala, Ninon, Engilberge, Sylvain, Gorel, Alexander, Signor, Luca, Teulon, Jean-Marie, Hilpert, Mario, Foucar, Lutz, Bielecki, Johan, Bean, Richard, de Wijn, Raphael, Sato, Tokushi, Kirkwood, Henry, Letrun, Romain, Batyuk, Alexander, Snigireva, Irina, Fenel, Daphna, Schubert, Robin, Canfield, Ethan J., Alba, Mario M., Laporte, Frédéric, Després, Laurence, Bacia, Maria, Roux, Amandine, Chapelle, Christian, Riobé, François, Maury, Olivier, Ling, Wai Li, Boutet, Sébastien, Mancuso, Adrian, Gutsche, Irina, Girard, Eric, Barends, Thomas R. M., Pellequer, Jean-Luc, Park, Hyun-Woo, Laganowsky, Arthur D., Rodriguez, Jose, Burghammer, Manfred, Shoeman, Robert L., Doak, R. Bruce, Weik, Martin, Sauter, Nicholas K., Federici, Brian, Cascio, Duilio, Schlichting, Ilme, Colletier, Jacques-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334358/
https://www.ncbi.nlm.nih.gov/pubmed/35902572
http://dx.doi.org/10.1038/s41467-022-31746-x