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How Does Our Knowledge on the Na(+)/H(+) Exchanger NHE1 Obtained by Biochemical and Molecular Analyses Keep up With Its Recent Structure Determination?

Na(+)/H(+) exchangers are membrane transporters conserved in all living systems and therefore are assumed to be amongst the most ancestral molecular devices that equipped the first protocells. Following the cloning and sequencing of its gene, the mammalian NHE1, that regulates pH and volume in all c...

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Detalles Bibliográficos
Autores principales: Poet, Mallorie, Doyen, Denis, Van Obberghen, Emmanuel, Jarretou, Gisèle, Bouret, Yann, Counillon, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334524/
https://www.ncbi.nlm.nih.gov/pubmed/35910559
http://dx.doi.org/10.3389/fphys.2022.907587