Cargando…

How Does Our Knowledge on the Na(+)/H(+) Exchanger NHE1 Obtained by Biochemical and Molecular Analyses Keep up With Its Recent Structure Determination?

Na(+)/H(+) exchangers are membrane transporters conserved in all living systems and therefore are assumed to be amongst the most ancestral molecular devices that equipped the first protocells. Following the cloning and sequencing of its gene, the mammalian NHE1, that regulates pH and volume in all c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poet, Mallorie, Doyen, Denis, Van Obberghen, Emmanuel, Jarretou, Gisèle, Bouret, Yann, Counillon, Laurent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334524/ https://www.ncbi.nlm.nih.gov/pubmed/35910559 http://dx.doi.org/10.3389/fphys.2022.907587

Ejemplares similares

Biological fractionation of lithium isotopes by cellular Na(+)/H(+) exchangers unravels fundamental transport mechanisms
por: Poet, Mallorie, et al.
Publicado: (2023)

Intracellular pH Control by Membrane Transport in Mammalian Cells. Insights Into the Selective Advantages of Functional Redundancy
por: Doyen, Denis, et al.
Publicado: (2022)

The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility
por: Monet, Michael, et al.
Publicado: (2016)

On the Role of the Difference in Surface Tensions Involved in the Allosteric Regulation of NHE-1 Induced by Low to Mild Osmotic Pressure, Membrane Tension and Lipid Asymmetry
por: Pang, Vincent, et al.
Publicado: (2012)

Pyrazine ring-based Na(+)/H(+) exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1
por: Rolver, Michala G., et al.
Publicado: (2020)

Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress
por: Melis, Nicolas, et al.
Publicado: (2023)

Mechanisms of the Regulation of the Intestinal Na(+)/H(+)Exchanger NHE3
por: He, Peijian, et al.
Publicado: (2010)

Capturing Intracellular pH Dynamics by Coupling Its Molecular Mechanisms within a Fully Tractable Mathematical Model
por: Bouret, Yann, et al.
Publicado: (2014)

Na(+)/H(+) exchanger NHE1 and NHE2 have opposite effects on migration velocity in rat gastric surface cells
por: Paehler vor der Nolte, Anja, et al.
Publicado: (2017)

Expression profile of genes regulated by activity of the Na-H exchanger NHE1
por: Putney, Luanna K, et al.
Publicado: (2004)

Endosomal Na(+)/H(+) exchanger NHE5 influences MET recycling and cell migration
por: Fan, Steven Hung-Yi, et al.
Publicado: (2016)

Metformin Inhibits Na(+)/H(+) Exchanger NHE3 Resulting in Intestinal Water Loss
por: Han, Yiran, et al.
Publicado: (2022)

Rainbow Trout (Oncorhynchus mykiss) Na(+)/H(+) Exchangers tNhe3a and tNhe3b Display Unique Inhibitory Profiles Dissimilar from Mammalian NHE Isoforms
por: Blair, Salvatore, et al.
Publicado: (2021)

Role of the Na(+)/H(+) exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines
por: Li, Xiao C, et al.
Publicado: (2015)

Dynamic Na(+)/H(+) exchanger 1 (NHE1) – calmodulin complexes of varying stoichiometry and structure regulate Ca(2+)-dependent NHE1 activation
por: Sjøgaard-Frich, Lise M, et al.
Publicado: (2021)

Inhibition and Redistribution of NHE3, the Apical Na(+)/H(+) Exchanger, by Clostridium difficile Toxin B
por: Hayashi, Hisayoshi, et al.
Publicado: (2004)

The mammalian Na+/H+ antiporters NHE-1, NHE-2, and NHE-3 are electroneutral and voltage independent, but can couple to an H+ conductance
Publicado: (1995)

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1
por: Denker, Sheryl P., et al.
Publicado: (2002)

Loss of the NHE2 Na(+)/H(+) Exchanger in Mice Results in Dilation of Folliculo-Stellate Cell Canaliculi
por: Miller, Marian L., et al.
Publicado: (2011)

Phosphorylation and Activation of the Plasma Membrane Na(+)/H(+) Exchanger (NHE1) during Osmotic Cell Shrinkage
por: Rigor, Robert R., et al.
Publicado: (2011)

Translocation of the Na(+)/H(+) exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signalling
por: Lawrence, Scott P., et al.
Publicado: (2010)

Endothelial Na(+)/H(+) exchanger NHE1 participates in redox-sensitive leukocyte recruitment triggered by methylglyoxal
por: Qadri, Syed M, et al.
Publicado: (2014)

Endosomal pH in neuronal signaling and synaptic transmission: role of Na(+)/H(+) exchanger NHE5
por: Diering, Graham H., et al.
Publicado: (2014)

The Na(+)/H(+) Exchanger-3 (NHE3) Activity Requires Ezrin Binding to Phosphoinositide and Its Phosphorylation
por: Babich, Victor, et al.
Publicado: (2015)

The Na(+)/H(+) exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium
por: Schneider, Linda, et al.
Publicado: (2009)

Proximal tubule specific knockout of the Na(+)/H(+) exchanger NHE3: effects on bicarbonate absorption and ammonium excretion
por: Li, Hong C., et al.
Publicado: (2013)

Role of the Basolateral Na(+)/H(+) Exchanger-2 (NHE2) in Ionocytes of Seawater- Acclimated Medaka (Oryzias latipes)
por: Liu, Sian-Tai, et al.
Publicado: (2022)

The Physiological Function and Potential Role of the Ubiquitous Na(+)/H(+) Exchanger Isoform 8 (NHE8): An Overview Data
por: Bernardazzi, Claudio, et al.
Publicado: (2022)

Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9
por: Winklemann, Iven, et al.
Publicado: (2020)

Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na(+)/H(+) exchanger NHE5
por: Diering, Graham H., et al.
Publicado: (2011)

Steady-state Function of the Ubiquitous Mammalian Na/H Exchanger (NHE1) in Relation to Dimer Coupling Models with 2Na/2H Stoichiometry
por: Fuster, Daniel, et al.
Publicado: (2008)

Steady-state Function of the Ubiquitous Mammalian Na/H Exchanger (NHE1) in Relation to Dimer Coupling Models with 2Na/2H Stoichiometry
por: Fuster, Daniel, et al.
Publicado: (2009)

Positive feedback between Cdc42 activity and H(+) efflux by the Na-H exchanger NHE1 for polarity of migrating cells
por: Frantz, Christian, et al.
Publicado: (2007)

Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na(+)/H(+) exchanger NHE3 by glucocorticoids
por: He, Peijian, et al.
Publicado: (2011)

Expression of Actin-interacting Protein 1 Suppresses Impaired Chemotaxis of Dictyostelium Cells Lacking the Na(+)-H(+) Exchanger NHE1
por: Choi, Chang-Hoon, et al.
Publicado: (2010)

Keeping It Simple, Transport Mechanism and pH Regulation in Na(+)/H(+) Exchangers
por: Călinescu, Octavian, et al.
Publicado: (2014)

The Na(+) /H(+) exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells
por: Amith, Schammim Ray, et al.
Publicado: (2014)

Na(+)/H(+) exchanger NHE1 regulation modulates metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer cells
por: Amith, Schammim Ray, et al.
Publicado: (2016)

The Na(+/)H(+)-Exchanger NHE1 Regulates Extra- and Intracellular pH and Nimodipine-sensitive [Ca(2+)](i) in the Suprachiasmatic Nucleus
por: Cheng, Pi-Cheng, et al.
Publicado: (2019)

The Sodium/Proton Exchanger NHE8 Regulates Late Endosomal Morphology and Function
por: Lawrence, Scott P., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_e02ci877r238ka2vfc6ofj8p8e