Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron

SARS-CoV-2 variants with adaptive mutations have continued to emerge, causing fresh waves of infection even amongst vaccinated population. The development of broad-spectrum antivirals is thus urgently needed. We previously developed two hetero-bivalent nanobodies (Nbs), aRBD-2-5 and aRBD-2-7, with p...

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Detalles Bibliográficos
Autores principales: Ma, Huan, Zhang, Xinghai, Zheng, Peiyi, Dube, Peter H., Zeng, Weihong, Chen, Shaohong, Cheng, Qingyu, Yang, Yunru, Wu, Yan, Zhou, Junhui, Hu, Xiaowen, Xiang, Yan, Zhang, Huajun, Chiu, Sandra, Jin, Tengchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334538/
https://www.ncbi.nlm.nih.gov/pubmed/35906408
http://dx.doi.org/10.1038/s41422-022-00700-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334538/
https://www.ncbi.nlm.nih.gov/pubmed/35906408
http://dx.doi.org/10.1038/s41422-022-00700-3

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