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Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron
SARS-CoV-2 variants with adaptive mutations have continued to emerge, causing fresh waves of infection even amongst vaccinated population. The development of broad-spectrum antivirals is thus urgently needed. We previously developed two hetero-bivalent nanobodies (Nbs), aRBD-2-5 and aRBD-2-7, with p...
Autores principales: | Ma, Huan, Zhang, Xinghai, Zheng, Peiyi, Dube, Peter H., Zeng, Weihong, Chen, Shaohong, Cheng, Qingyu, Yang, Yunru, Wu, Yan, Zhou, Junhui, Hu, Xiaowen, Xiang, Yan, Zhang, Huajun, Chiu, Sandra, Jin, Tengchuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334538/ https://www.ncbi.nlm.nih.gov/pubmed/35906408 http://dx.doi.org/10.1038/s41422-022-00700-3 |
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