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Development of a novel light-up probe for detection of G-quadruplexes in stress granules

G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small molecules has been poorly investigated. Herein, we present a fluorescent light-up probe with the ability to selectively stabilize G4s and...

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Detalles Bibliográficos
Autores principales: Iida, Keisuke, Suzuki, Natsumi, Sasaki, Ayano, Ishida, Shunsuke, Arai, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334577/
https://www.ncbi.nlm.nih.gov/pubmed/35902691
http://dx.doi.org/10.1038/s41598-022-17230-y