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Prime editor-mediated correction of a pathogenic mutation in purebred dogs

Canine hip dysplasia (HD) is a multifactorial disease caused by interactions between genetic and environmental factors. HD, which mainly occurs in medium- to large-sized dogs, is a disease that causes severe pain and requires surgical intervention. However, the procedure is not straight-forward, and...

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Detalles Bibliográficos
Autores principales: Kim, Dong Ern, Lee, Ji Hye, Ji, Kuk Bin, Lee, Eun Ji, Li, Chuang, Oh, Hyun Ju, Park, Kang Sun, Lee, Seung Hoon, Koo, Okjae, Kim, Min Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334597/
https://www.ncbi.nlm.nih.gov/pubmed/35902672
http://dx.doi.org/10.1038/s41598-022-17200-4