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Mesenchymal stem cells exert renoprotection via extracellular vesicle-mediated modulation of M2 macrophages and spleen-kidney network

Adipose-derived mesenchymal stem cells (ASCs) have shown therapeutic potentials against refractory diseases. However, the detailed therapeutic mechanisms remain unclear. Here, we report the therapeutic actions of human ASCs in nephritis, focusing on cellular dynamics and multi-organ networks. Intrav...

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Detalles Bibliográficos
Autores principales: Shimamura, Yuko, Furuhashi, Kazuhiro, Tanaka, Akihito, Karasawa, Munetoshi, Nozaki, Tomoya, Komatsu, Shintaro, Watanabe, Kenshi, Shimizu, Asuka, Minatoguchi, Shun, Matsuyama, Makoto, Sawa, Yuriko, Tsuboi, Naotake, Ishimoto, Takuji, Suzuki, Hiroshi I., Maruyama, Shoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334610/
https://www.ncbi.nlm.nih.gov/pubmed/35902687
http://dx.doi.org/10.1038/s42003-022-03712-2