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Deficiency of mature B cells does not alter the atherogenic response to castration in male mice

Testosterone deficiency in men is associated with increased atherosclerosis burden and increased cardiovascular risk. In male mice, testosterone deficiency induced by castration increases atherosclerosis as well as mature B cell numbers in spleen. As B cells are potentially pro-atherogenic, we hypot...

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Detalles Bibliográficos
Autores principales: Wilhelmson, Anna S., Johansson, Inger, Fogelstrand, Linda, Fagman, Johan Bourghardt, Arnal, Jean-Francois, Karlsson, Mikael C. I., Tivesten, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334632/
https://www.ncbi.nlm.nih.gov/pubmed/35902665
http://dx.doi.org/10.1038/s41598-022-16846-4