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Deficiency of mature B cells does not alter the atherogenic response to castration in male mice
Testosterone deficiency in men is associated with increased atherosclerosis burden and increased cardiovascular risk. In male mice, testosterone deficiency induced by castration increases atherosclerosis as well as mature B cell numbers in spleen. As B cells are potentially pro-atherogenic, we hypot...
Autores principales: | Wilhelmson, Anna S., Johansson, Inger, Fogelstrand, Linda, Fagman, Johan Bourghardt, Arnal, Jean-Francois, Karlsson, Mikael C. I., Tivesten, Åsa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334632/ https://www.ncbi.nlm.nih.gov/pubmed/35902665 http://dx.doi.org/10.1038/s41598-022-16846-4 |
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