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The hexokinase “HKDC1” interaction with the mitochondria is essential for liver cancer progression

Liver cancer (LC) is the fourth leading cause of death from cancer malignancies. Recently, a putative fifth hexokinase, hexokinase domain containing 1 (HKDC1), was shown to have significant overexpression in LC compared to healthy liver tissue. Using a combination of in vitro and in vivo tools, we e...

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Detalles Bibliográficos
Autores principales: Khan, Md. Wasim, Terry, Alexander R., Priyadarshini, Medha, Ilievski, Vladimir, Farooq, Zeenat, Guzman, Grace, Cordoba-Chacon, Jose, Ben-Sahra, Issam, Wicksteed, Barton, Layden, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334634/
https://www.ncbi.nlm.nih.gov/pubmed/35902556
http://dx.doi.org/10.1038/s41419-022-04999-z