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IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation

OBJECTIVE: Androgen deprivation therapy (ADT) is still the principal treatment option for prostate cancer (PCa). In addition to reactivation of androgen receptor signaling, the resistance of PCa to apoptosis during ADT also contributes to castration resistant PCa (CRPC). A previous study reported th...

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Detalles Bibliográficos
Autores principales: Feng, Tingting, Wang, Jing, Cheng, Kai, Lu, Qiqi, Zhao, Ru, Wang, Shiguan, Zhang, Qingyun, Ge, Luna, Pan, Jihong, Song, Guanhua, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334759/
https://www.ncbi.nlm.nih.gov/pubmed/34652890
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0583