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Dual-targeted lung cancer therapy via inhalation delivery of UCNP-siRNA-AS1411 nanocages

OBJECTIVE: Although great progress has been made in the field of siRNA gene therapy, safe, efficient, and targeted delivery of siRNA are still major challenges in siRNA therapeutics. METHODS: We developed an up-conversion nanoparticle-based nanocage system. This system protected the siRNA from being...

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Detalles Bibliográficos
Autores principales: Han, Yu, Yang, Yuming, Sun, Qiuyang, Li, Bin, Yue, Caixia, Liu, Yanlei, de la Fuente, Jesús M., Cui, Daxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334765/
https://www.ncbi.nlm.nih.gov/pubmed/34427999
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0416