Metformin Alleviates LPS-Induced Acute Lung Injury by Regulating the SIRT1/NF-κB/NLRP3 Pathway and Inhibiting Endothelial Cell Pyroptosis

Acute respiratory distress syndrome (ARDS), a devastating complication of numerous conditions, is often associated with high mortality. It is well known that endothelial cell (EC) damage and inflammation are vital processes in the pathogenesis of ARDS. Nevertheless, the mechanisms of EC damage are l...

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Detalles Bibliográficos
Autores principales: Zhang, Yunqian, Zhang, Hui, Li, Siyuan, Huang, Kai, Jiang, Lai, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334876/
https://www.ncbi.nlm.nih.gov/pubmed/35910360
http://dx.doi.org/10.3389/fphar.2022.801337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334876/
https://www.ncbi.nlm.nih.gov/pubmed/35910360
http://dx.doi.org/10.3389/fphar.2022.801337

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