The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements

Aberrant expression of Ecotropic Viral Integration Site 1 (EVI1) is a hallmark of acute myeloid leukemia (AML) with inv(3) or t(3;3), which is a disease subtype with especially poor outcome. In studying transcriptomes from AML patients with chromosome 3q rearrangements, we identified a significant u...

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Detalles Bibliográficos
Autores principales: Grasedieck, Sarah, Cabantog, Ariene, MacPhee, Liam, Im, Junbum, Ruess, Christoph, Demir, Burcu, Sperb, Nadine, Rücker, Frank G., Döhner, Konstanze, Herold, Tobias, Pollack, Jonathan R., Bullinger, Lars, Rouhi, Arefeh, Kuchenbauer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article - Acute Myeloid Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335095/
https://www.ncbi.nlm.nih.gov/pubmed/34854277
http://dx.doi.org/10.3324/haematol.2020.276048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335095/
https://www.ncbi.nlm.nih.gov/pubmed/34854277
http://dx.doi.org/10.3324/haematol.2020.276048

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