B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a frequent lymphoproliferative disorder of B cells. Although inhibitors targeting signal proteins involved in B-cell antigen receptor (BCR) signaling constitute an important part of the current therapeutic protocols for CLL patients, the exact role of BCR signal...

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Detalles Bibliográficos
Autores principales: Schmid, Vera Kristin, Khadour, Ahmad, Ahmed, Nabil, Brandl, Carolin, Nitschke, Lars, Rajewsky, Klaus, Jumaa, Hassan, Hobeika, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Chronic Lymphocytic Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335107/
https://www.ncbi.nlm.nih.gov/pubmed/35021605
http://dx.doi.org/10.3324/haematol.2021.279924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335107/
https://www.ncbi.nlm.nih.gov/pubmed/35021605
http://dx.doi.org/10.3324/haematol.2021.279924

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