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cAMP and voltage modulate rat auditory mechanotransduction by decreasing the stiffness of gating springs

Hair cells of the auditory and vestibular systems transform mechanical input into electrical potentials through the mechanoelectrical transduction process (MET). Deflection of the mechanosensory hair bundle increases tension in the gating springs that open MET channels. Regulation of MET channel sen...

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Detalles Bibliográficos
Autores principales: Mecca, Andrew A., Caprara, Giusy A., Peng, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335186/
https://www.ncbi.nlm.nih.gov/pubmed/35858439
http://dx.doi.org/10.1073/pnas.2107567119