Elevated BICD2 DNA methylation in blood of major depressive disorder patients and reduction of depressive-like behaviors in hippocampal Bicd2-knockdown mice

Major depressive disorder (MDD) is a prevalent and devastating mental illness. To date, the diagnosis of MDD is largely dependent on clinical interviews and questionnaires and still lacks a reliable biomarker. DNA methylation has a stable and reversible nature and is likely associated with the cours...

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Detalles Bibliográficos
Autores principales: Xiu, Jianbo, Li, Jiayu, Liu, Zeyue, Wei, Hui, Zhu, Caiyun, Han, Rongrong, Liu, Zijing, Zhu, Wanwan, Shen, Yan, Xu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335189/
https://www.ncbi.nlm.nih.gov/pubmed/35858435
http://dx.doi.org/10.1073/pnas.2201967119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335189/
https://www.ncbi.nlm.nih.gov/pubmed/35858435
http://dx.doi.org/10.1073/pnas.2201967119

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